Voriconazole Level VORICON

Synonyms

Allscripts (AEHR) Order Name

Voriconazole Level

Sunrise Clinical Manager (SCM) Order Name

Voriconazole, Trough

Clinical Info

Monitoring trough levels of voriconazole is suggested in patients with impaired liver function, patients with pharmacogenomics polymorphisms associated with lower metabolism of voriconazole (e.g. genotypes CYP2C19*2 and CYP2C19*3), and in patients taking other medications that affect CYP2C19 activity.

Specimen Type

Blood

Container

Red Top Tube

Collection Instructions

Container/Tube: Red Top Tube
Specimen: 1 mL serum (0.5 mL min)
Transport Temperature: Frozen
Stability: 14 Frozen
Collection
Transfer separated serum or plasma to a plastic transport tube. Do not use a gel barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage times, the decrease in drug level due to absorption may be clinically significant.

Transport Instructions

Frozen

Specimen Stability

14 Frozen
Collection
Transfer separated serum or plasma to a plastic transport tube. Do not use a gel barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and stor

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Days Performed

2 - 3 Days

Performing Laboratory

Viracor-Eurofins

CPT

80285
 
LOINC Code: 38370-3

PDM

5960045

Result Interpretation

0.1 – 10 mcg/mL

Forms