VMA and HVA, Child VMAHVA

Synonyms

Allscripts (AEHR) Order Name

VMA and HVA, Child

Sunrise Clinical Manager (SCM) Order Name

VMA and HVA, Child

Clinical Info

First preferred test for screening for catecholamine-secreting tumors in a random urine specimen when requesting both homovanillic acid and vanillylmandelic acid
Supporting a diagnosis of neuroblastoma
Monitoring patients with a treated neuroblastoma

Specimen Type

Urine

Container

Urine Cntr

Collection Instructions

Container/Tube: Sterile cup
Volume: 5 mL random urine (2 mL min)
Transport Temperature: Refrigerated
Stability: 28 days refrigerated
180 Days Frozen
Collection Instructions:
1. Collect a random urine specimen.
2. Adjust urine pH to 1 to 5 with 50% acetic or hydrochloric
acid.
Patient Preparation: Administration of L-dopa may falsely
increase homovanillic acid and vanillylmandelic acid results; it
should be discontinued 24 hours prior to and during collection of
specimen.

Transport Instructions

Refrigerated

Specimen Stability

28 days refrigerated
180 Days Frozen

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Days Performed

Monday through Friday; 8 a.m.

Performing Laboratory

Mayo Medical Laboratories

CPT

83150-HVA
84585-VMA

LOINC Code: 90250-2

PDM

5908565

Result Interpretation

VANILLYLMANDELIC ACID

<1 year: <25.0 mg/g creatinine

1 year: <22.5 mg/g creatinine

2-4 years: <16.0 mg/g creatinine

5-9 years: <12.0 mg/g creatinine

10-14 years: <8.0 mg/g creatinine

≥15 years: &

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