Vedolizumab and Anti-Vedolizumab Ab VEDOLIZ

Synonyms

Allscripts (AEHR) Order Name

Vedolizumab and Anti-Vendolizumab AB

Sunrise Clinical Manager (SCM) Order Name

Vedolizumab and Anti-Vedolizumab AB

Clinical Info

Provides serum concentrations of vedolizumab and anti-vedolizumab antibodies in order to optimize treatment and facilitate clinical decision-making.

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube: Gold Top Tube or Red Top Tube
Specimen: 2 mL serum ( 1 mL min)
Transport Temperature: Refrigerated

Transport Instructions

Specimen Stability

14 Days Room Temperature
14 Days Refrigerated
14 Days Frozen

Methodology

Electrochemiluminescence Immunoassay (ECLIA)

Days Performed

TAT: 9-16 Days

Performing Laboratory

LabCorp

CPT

80280
82397
LOINC Code 90794-9

PDM

1759547

Result Interpretation

See Report

   In the absence of anti-vedolizumab antibodies, the vedolizumab drug level reflects the total vedolizumab concentration. In the presence of anti-vedolizumab antibodies, the vedolizumab concentration reflects the antibody-unbound fraction of vedolizumab.
The presence of vedolizumab drug, even at concentrations well above target treatment levels , does not interfere with anti-vedolizumab antibody measurement. All positive anti-vedolizumab antibody results are verified by a confirmatory test.
Limitations
Drug half-life should be taken into consideration when interpreting concentrations measured in non-trough collections.

Forms

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