Test Code ULTRASCR Second Trimester Maternal Sequential Screen
Performing Laboratory
NTD Eurofins
Reference Values
See Reference Report
Test Classification and CPT Coding
84704
82677
82105
86336
Day(s) and Time(s) Performed
Monday- Friday
Physician Office Specimen Requirements
Container/Tube: Gold top tube
Specimen: 2 ml serum ( 1 ml min)
Transport Temperature: Room Temperature
Collection Requirments:
Pateints MUST have had the first trimester screen done though NTD
Test includes: AFP, free beta hCG, uE3 and inhibin-A
Performed pregnancy time frame: 15 weeks 0 days - 21 weeks 6 days
Computer Interface Code
PDM # 5900732
Used For
Part 2 of the Sequential Screen | Fß is performed in the second trimester of pregnancy, between 15 weeks and 21 weeks, 6 days gestation. This part of the test analyzes 4 biomarkers found in the mother's serum - alpha-fetoprotein (AFP), free beta hCG, unconjugated estriol, and inhibin-A. When the measurements from Part 2 are combined with those from Part 1, 95% of Down syndrome cases are detected at a 5.8% false positive rate and 95% of trisomy 18 and trisomy 13 cases are detected at a 0.3% false positive rate. Sequential Screen | Fß also screens for ONTDs, which can only be done in the second trimester. This test detects 90% of cases of open spina bifida and 98% of cases of anencephaly