Phospholipase A2 Resp Ab PLA2R

Synonyms
Allscripts (AEHR) Order Name	Phospholipase A2 Receptor Ab
Sunrise Clinical Manager (SCM) Order Name	Not Orderable
Clinical Info	The anti-PLA2R ELISA (IgG) test kit is intended for the qualitative or semiquantitative determination of IgG class autoantibodies against phospholipase A2 receptor (PLA2R) in human serum.1 It is used as an aid in the diagnosis of primary membranous glomerulonephritis (pMGN), in conjunction with other laboratory and clinical findings. Limitations The test is not a standalone test but an adjunct to other clinical information. A diagnosis of membranous nephropathy (MN) should not be made on a single test result. The clinical symptoms, results on physical examination, and laboratory tests (eg, serological tests), when appropriate, should always be taken into account when considering the diagnosis of primary versus secondary MN. Absence of circulating PLA2R autoantibodies does not rule out a diagnosis of PLA2R-related membranous nephropathy. Clinical evidence must not be overruled in favor of a numerical value. The assay has not been demonstrated to be effective for monitoring the stage of disease or its response to treatment. Borderline samples should be considered as potentially positive and retested.
Specimen Type
Container	Gold Top Tube
Collection Instructions	Container/Tube: Gold Top tube or Red Top Tube Specimen: 0.5 mL serum (0.2 mL min) Transport Temperature: Refrigerated Stability: 14 Days Room Temperature, Refrigerated or Frozen
Transport Instructions	Refrigerated
Specimen Stability	14 Days Room Temperature, Refrigerated or Frozen
Methodology	Enzyme-linked immunosorbent assay (ELISA)
Days Performed
Performing Laboratory	LabCorp
CPT	83516 LOINC Code: 73737-9
PDM	1659078
Result Interpretation Negative <14.0 RFU/mL Borderline 14.0 - 19.9 RU/mL Positive >19.9 RU/mL TAT: 4 - 9 Days
Forms