N-Methylhistamine, Random Ur NMHR

Synonyms

Allscripts (AEHR) Order Name

N-Methylhistamine, Random Urine

Sunrise Clinical Manager (SCM) Order Name

N-Methylhistamine, Random Urine

Clinical Info

Monitoring therapeutic progress in conditions that are associated with secondary, localized, low-grade persistent, mast-cell proliferation and activation such as interstitial cystitis

Specimen Type

Container

Urine Cup

Collection Instructions

Specimen Type: Urine
Patient Preparation: Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as these medications increase N-methylhistamine (NMH) levels.
Supplies: Aliquot Tube, 5 mL (T465)
Container/Tube: Plastic vial, 5-mL
Specimen Volume: 5 mL
Collection Instructions:
1. Collect a random urine specimen within a few hours of symptom onset.
2. No preservative.
Specimen Minimum Volume: 3 mL
Specimen Stability Information:

Specimen Type	Temperature	Time	Special Container
Urine	Refrigerated (preferred)	28 days
	Frozen	28 days
	Ambient	14 days

Transport Instructions

Specimen Stability

Methodology

NMHR1: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CRETR: Enzymatic Colorimetric Assay

Days Performed

Tuesday, Thursday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT

82542
82570

PDM

2059266

Result Interpretation

N-METHYLHISTAMINE
0-5 years: 120-510 mcg/g creatinine
6-16 years: 70-330 mcg/g creatinine
>16 years: 30-200 mcg/g creatinine


CREATININE
Males: 930-2955 mg/24 hours
Females: 603-1783 mg/24 hours
Reference values have not been established for patients who are less than 18 years of age

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