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Test Code NMDAGCSF N-methyl-D-Aspartate Receptor Ab, IgG, CSF with Reflex to Titer

Performing Laboratory

ARUP Laboratories


Semi-Quantitative Indirect Fluorescent Antibody



This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Specimen Required

Container/Tube: Standard transport tube

Specimen: 0.5 mL CSF( 0.2 mL min)

Transport Temperature: Refrigerated.



Reference Values

< 1:1


If NMDA antibody IgG is positive, then an NMDA antibody IgG titer is reported. Additional charges apply.

Test Classification and CPT Coding

86255; if reflexed, add 86256


LOINC: 80220-7


Test performed Tuesday and Friday

TAT 2 - 6 Days

Day(s) and Time(s) Performed

Tuesday and Friday

Useful For

Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.  

Computer Interface Code

PDM #  1759244