Test Code NMDAGCSF N-methyl-D-Aspartate Receptor Ab, IgG, CSF with Reflex to Titer
Performing Laboratory
ARUP Laboratories
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Specimen Required
Container/Tube: Standard transport tube
Specimen: 0.5 mL CSF( 0.2 mL min)
Transport Temperature: Refrigerated.
Note:
Reference Values
< 1:1
If NMDA antibody IgG is positive, then an NMDA antibody IgG titer is reported. Additional charges apply.
Test Classification and CPT Coding
86255; if reflexed, add 86256
LOINC: 80220-7
Test performed Tuesday and Friday
TAT 2 - 6 Days
Day(s) and Time(s) Performed
Tuesday and Friday
Useful For
Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.
Computer Interface Code
PDM # 1759244