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Test Code ETAPROTEIN 14-3-3 eta Protein

Methodology

Enzyme Linked Immunosorbent Assay (ELISA)

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Performing Laboratory

Quest Diagnostics Nichols Inst San Juan Capistrano

Sent to Chantilly, VA

Specimen Required

Container/Tube: Gold top tube

Specimen: 1 mL serum ( 0.5 mL min)

Transport Temperature: Refrigerated

Stability:  Room Temperature and Refrigerated  7 Days

                 Frozen  21 Days

Reference Values

< 0.2  ng/mL

Test Classification and CPT Coding

83520

 

Loinc Code: 75880-5

Conputer Interface Code

PDM #  1859784

Used For

The 14-3-3η protein appears to contribute to the pathologic process of joint erosion and, as such, is an emerging biomarker of joint damage in rheumatoid arthritis (RA) and psoriatic arthritis. Concentrations are significantly higher in people with active joint disease than in those with inactive RA or psoriasis without arthritis. Measurement of 14-3-3η complements RF and CCP antibody tests and may improve diagnostic sensitivity.