Test Code EHISTO Entamoeba histolytica Antibody, Serum
Additional Codes
Mayo Test ID |
---|
SAM |
Reporting Name
E. histolytica Ab, SUseful For
As an adjunct in the diagnosis of extraintestinal amebiasis, especially liver abscess
Performing Laboratory

Specimen Type
SerumAdvisory Information
Direct detection of Entamoeba histolytica in fecal specimens is recommended to diagnose intestinal amebiasis. See OAP / Ova and Parasite, Concentrate and Permanent Smear, Microscopy, Feces or OAPNS / Ova and Parasite, Microscopy, Varies.
Shipping Instructions
Specimen Required
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 0.5 mL
Specimen Minimum Volume
0.15 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Frozen (preferred) | 30 days | |
Refrigerated | 7 days |
Reference Values
Negative
Reference values apply to all ages.
Day(s) and Time(s) Performed
Tuesday, Thursday; 9 a.m.
Test Classification
This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86753
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
SAM | E. histolytica Ab, S | 22285-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
9049 | E. histolytica Ab, S | 22285-1 |
Clinical Information
Amebiasis is an infection by the protozoan parasite, Entamoeba histolytica. The infection is acquired by ingestion of cysts in fecally contaminated food or water; excystation and infection occur in the large intestine. After excystation, trophozoites attach to the intestinal wall and liberate extracellular enzymes that enable invasion of the mucosa and spread to other organs, especially the liver and lung where abscesses develop.
Amebiasis (or amebic dysentery) can cause bloody diarrhea accompanied by fever and prostration. White and red blood cells are found in the stool. Liver abscess can develop several weeks to months later producing hepatomegaly and fever.
Pathogenic (E histolytica) and nonpathogenic (Entamoeba dispar) species of Entamoeba occur. Additionally, some of those infected with pathogenic strains are asymptomatic cyst carriers.
Serology may be particularly useful in supporting the diagnosis of amebic liver abscess in patients without a definite history of intestinal amebiasis and who have not spent substantial periods of time in endemic areas.
Analytic Time
Same day/1 dayReject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
NY State Approved
YesMethod Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Forms
If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.
Computer Interface Code
PDM # 5901515