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Test Code EEPC Eastern Equine Encephalitis Antibody Panel, IgG and IgM, Spinal Fluid

Useful For

Aiding the diagnosis of Eastern equine encephalitis in spinal fluid specimens

Method Name

Immunofluorescence Assay (IFA)

Reporting Name

East Equine Enceph Ab Panel, CSF

Specimen Type

CSF


Advisory Information


This test is not available for specimens originating in New York.



Specimen Required


Container/Tube: Sterile vial

Specimen Volume: 0.5 mL


Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 14 days
  Frozen  14 days

Clinical Information

Eastern equine encephalitis (EEE) is within the alphavirus group. It is a low-prevalence cause of human disease in the Eastern and Gulf Coast states. EEE is maintained by a cycle of mosquito/wild bird transmission, peaking in the summer and early fall, when man may become an adventitious host. The most common clinically apparent manifestation is a mild undifferentiated febrile illness, usually with headache.

 

Central nervous system involvement is demonstrated in only a minority of infected individuals, and is more abrupt and more severe than with other arboviruses, with children being more susceptible to severe disease. Fatality rates are approximately 70% EEE.

 

Infections with arboviruses can occur at any age. The age distribution depends on the degree of exposure to the particular transmitting arthropod, relating to age, sex, and occupational, vocational, and recreational habits of the individuals. Once humans have been infected, the severity of the host response may be influenced by age.

Reference Values

IgG: <1:10

IgM: <1:10

Reference values apply to all ages.

Day(s) and Time(s) Performed

May through October: Monday through Friday; 9 a.m.

November through April: Monday, Wednesday, Friday; 9 a.m.

Analytic Time

Same day/1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86652 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EEPC East Equine Enceph Ab Panel, CSF 69035-4

 

Result ID Test Result Name Result LOINC Value
26369 East Equine Enceph Ab, IgG, CSF 10897-7
26370 East Equine Enceph Ab, IgM, CSF 10899-3

NY State Approved

No