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Test Code ECHINO Echinococcus Antibody, IgG, Serum

Important Note

Mayo test code ECHNO

Useful For

Detection of antibodies to Echinococcus species, including E multilocularis and E granulosus

Method Name

Enzyme Immunoassay (EIA)

Reporting Name

Echinococcus Ab, IgG, S

Specimen Type


Specimen Required


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.50 mL

Specimen Minimum Volume

0.20 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 30 days
  Frozen  30 days

Clinical Information

Echinococcosis, also referred to as hydatidosis or hydatid disease, is one of the 17 neglected tropical diseases recognized by the World Health Organization, and affects over 1 million people worldwide. Echinococcus species are tapeworms or cestodes and 2 main species infect humans: Echinococcus granulosus and Echinococcus multilocularis.


With respect to geographic distribution, E granulosus can be found worldwide, but more frequently in rural, grazing areas where dogs may feed on deceased,infected sheep or cattle. E multilocularis is largely localized to the northern hemisphere. The definitive hosts for E granulosus are dogs or other canids, while the definitive host for E multilocularis are foxes and, to a much lesser extent, canids. Echinococcus tapeworms reside in the small intestine of definitive hosts and release eggs that are passed in the feces and ingested by an intermediate host, typically sheep or cattle in the case of E granulosus or small rodents for E multilocularis. The eggs hatch in the small bowel, releasing an oncosphere, which penetrates the intestinal wall and migrates through the circulatory system to various organs where it will develop into a cyst that gradually enlarges producing protoscolicies and daughter cysts that fill the interior. The definitive host becomes infected following ingestion of these infectious cysts. Humans become accidentally infected following ingestion of Echinococcus eggs.


In humans, E granulosus (cystic echinococcal disease) cysts typically develop in the lungs and liver and the infection may remain silent or latent for years (5-20 years) prior to cyst enlargement and symptom manifestation. Symptomatic manifestations include chest pain, hemoptysis and cough for pulmonary involvement and abdominal pain and biliary duct obstruction for liver infection. E multilocularis (alveolar echinococcal disease) infections manifest more rapidly than those of E granulosus, and manifests similar to a rapidly growing, destructive tumor resulting in abdominal pain and biliary obstruction. Rupture of cysts can produce fever, urticaria and anaphylactic shock.


Diagnosis of echinococcal infections relies on characteristic finding by ultrasound or other imaging techniques and serologic findings. Fine needle aspirates of cystic fluid may be performed; however they carry the risk of cyst puncture and fluid leakage which may potentially lead to severe allergic reactions. Importantly, infected individuals do not shed eggs in stool.

Reference Values


Day(s) and Time(s) Performed

Tuesday, Thursday; 9 a. m.

Analytic Time

Same day/1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
ECHNO Echinococcus Ab, IgG, S 32171-1


Result ID Test Result Name Result LOINC Value
64985 Echinococcus Ab, IgG, S 32171-1

NY State Approved

Northwell Health Laboratories Additional Information:

Computer Interface Code

   PDM #  5903820