Test Code D LACT D-Lactate, Plasma
Additional Codes
Mayo Test ID |
---|
DLAC |
Reporting Name
D-Lactate, PUseful For
An adjunct to urine D-lactate (preferred) for the diagnosis of D-lactate acidosis
Performing Laboratory

Specimen Type
Plasma NaFl-KOxAdvisory Information
Urine is the preferred specimen for D-lactate determination, order DLAU / D-Lactate, Urine.
For determination of L-lactate (lactic acid), order LACS1 / Lactate, Plasma
Necessary Information
Specimen Required
Collection Container/Tube: Sodium Fluoride/Potassium Oxalate Tube, 2 mL (T275)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge, aliquot plasma in plastic vial, and freeze immediately .
Specimen Minimum Volume
0.55 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma NaFl-KOx | Frozen (preferred) | 365 days | |
Ambient | 7 days | ||
Refrigerated | 7 days |
Reference Values
0.0-0.25 mmol/L
Day(s) and Time(s) Performed
Varies
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
83605
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
DLAC | D-Lactate, P | 14045-9 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
8878 | D-Lactate, P | 14045-9 |
Clinical Information
D-lactate is produced by bacteria residing in the colon when carbohydrates are not completely absorbed in the small intestine. When large amounts of D-lactate are present, individuals can experience metabolic acidosis, altered mental status (from drowsiness to coma), and a variety of other neurologic symptoms, particularly dysarthria and ataxia.
D-lactic acidosis is typically observed in patients with a malabsorptive disorder, such as short-bowel syndrome, or following a jejunoileal bypass. In addition, healthy children presenting with gastroenteritis may also develop the critical presentation of D-lactic acidosis.
Routine lactic acid determinations in blood will not reveal abnormalities because most lactic acid assays measure only L-lactate. Accordingly, D-lactate analysis must be specifically requested (eg, this test). However, as D-lactate is readily excreted in urine, DLAU / D-Lactate, Urine is the preferred specimen for D-lactate determinations.
Analytic Time
4 daysReject Due To
Gross hemolysis | OK |
Gross lipemia | OK |
Gross icterus | OK |
NY State Approved
YesMethod Name
Enzymatic
Special Instructions
Computer Interface Code
PDM # 5910660