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Test Code COLLGN N-Telopeptides with Creatinine, Urine

Additional Codes

Sunrise Clinical Manager (SCM) Orderable:   N-Telepeptides w/Creatinine

AllScripts (AEHR) Orderable:  N-Telepeptides w/Creatinine (second void urine)

Performing Laboratory

Quest Nichols-Valencia


Calculation • Colorimetric

Reference Values


  18-29 years 12-99 nmol BCE/mmol creat
  30-59 years 9-60 nmol BCE/mmol creat
  Premenopausal 4-64 nmol BCE/mmol creat

Results are primarily used for monitoring the response to therapy. A value within the premenopausal reference range does not rule out osteoporosis nor the need for therapy.

Creatinine, Random, Urine

0-6 months 2-32 mg/dL
7-11 months   2-36 mg/dL
1-2 years 2-128 mg/dL
3-8 years 2-149 mg/dL
9-12 years 2-183 mg/dL
Male >12 years 20-370 mg/dL
Female >12 years 20-320 mg/dL


Test Classification and CPT Coding

82523 - collagen crosslinks

82570 - creatinine


Loinc: 14115-0

Useful For

NTx is useful to assess bone resorption in patients with metabolic bone disease. The test is also useful in monitoring therapy to slow or halt osteoporotic bone loss. A decline of 30% or more of NTx over a six-month period suggests effective therapy.

Computer Interface Code

PDM #  5900486

Physician Office Specimen Requirements

Container/Tube: Sterile leek-proof container

Specimen:   2 mL from a second-morning urine collection. Discard first-morning urine. No preservative.

Transport Temperature:  Refrigerated

Day(s) and Time(s) Performed

Tuesday,, Thursday and Saturday

TAT 2 - 5 Days