ASCA IgA and IgG Antibodies ASCA

Synonyms

Saccharomyces cerevisiae Abs, IgG, IgM

Allscripts (AEHR) Order Name

ASCA IgA/IgG Antibodies

Sunrise Clinical Manager (SCM) Order Name

ASCA IgA/IgG Antibodies

Clinical Info

Antibodies to Saccharomyces cerevisiae are found in approximately 75% of patients with Crohn's disease, 15% of patients with ulcerative colitis, and 5% of the healthy population. High titers of antibody increase the likelihood of disease, and specifically Crohn's disease, and are associated with more aggressive disease.

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube:  Gold-top tube(s)
Specimen:  1 mL of serum
Transport Temperature:  Refrigerate

Transport Instructions

Refrigerate

Specimen Stability

Methodology

Enzyme-Linked Immunosorbent Assay (ELISA)

Days Performed

Two times per week

Performing Laboratory

Northwell Health Laboratories

CPT

83520 x 2

PDM

5702020

Result Interpretation

ASCA IgA or ACSA IgG
Negative:  ≤20.0 Units
Equivocal:  20.1-24.9 Units
Weak positive:  25.0-34.9 Units
Positive:  ≥35.0 Units

Forms