Acetylcholine Receptor Binding Ab ACRAB

Synonyms

Allscripts (AEHR) Order Name

Acetylcholine Receptor Binding Antibody

Sunrise Clinical Manager (SCM) Order Name

Acetylcholine Receptor Binding Antibody

Clinical Info

This assay is the primary test for confirming the diagnosis of acquired myasthenia gravis.
 

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube:  Gold-top tube(s)
Specimen:  1 mL of serum(0.3 mL min)
                       No isotopes administered 24 hours prior to venipuncture
Transport Temperature:  Refrigerate
Stability:  14 days Room Temperature, Refrigerated, Frozen
Rejection: Gross hemolysis; gross icterus; gross lipemia
                

Transport Instructions

Refrigerate

Specimen Stability

14 days Room Temperature, Refrigerated, Frozen
Rejection: Gross hemolysis; gross icterus; gross lipemia
                

Methodology

This assay measures antibodies that precipitate solublized muscle AChR that has been complexed with radiolabeled alpha-bungarotoxin (?BTX). Antibodies that bind to the receptor regions that are not sterically blocked by the ?BTX are detected.

Days Performed

Performing Laboratory

LabCorp

CPT

83519
 
LOINC: 11034-6

PDM

5900210

Result Interpretation

Negative: 0.00−0.24 nmol/L
 Borderline: 0.25−0.40 nmol/L
 Positive: >0.40 nmol/L

Forms