Test Code ACMAB Acetylcholine Modulating Antibody, Serum
Performing Laboratory
LabCorp Burlington, NC
Methodology
Cell culture-based radioimmunoassay (RIA)
TAT: 7 -8 Days
Specimen Requirements
Container/Tube: Gold-top tube(s)
Specimen: 0.5 mL serum (0.3 mL minimum)
Transport Temperature: Refrigerate
Stability: 7 Days Room Temperature
14 days Refrigerated
2 Months Frozen
Reference Values
Negative: <21 %
Equivocal: 21 - 25 %
Positive: >25 %
Test Classification and CPT Coding
83519
LOINC Code: 30192-9
LONIC: 11562-6
Computer Interface Code
PDM # 5901705
Useful For
Diagnose myasthenia gravis (MG); monitor response to treatment of myasthenia gravis
Limitations
False positives can occur in patients with serum drawn within 48 hours of administration of general anesthesia and muscle relaxants. Antibodies to α-bungarotoxin (α-BTX) may sometimes be found in patients treated with snake venom. Recently administered radioisotopes may interfere with the assay in unpredictable ways. Acetylcholine receptor autoantibodies are not typically found in congenital myasthenia gravis.