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Test Code ACMAB Acetylcholine Modulating Antibody, Serum

Performing Laboratory

LabCorp Burlington, NC

Methodology

Cell culture-based radioimmunoassay (RIA)

 

TAT: 7 -8 Days

Specimen Requirements

Container/Tube:  Gold-top tube(s)

Specimen:  0.5 mL serum (0.3 mL minimum)

Transport Temperature:  Refrigerate

Stability:   7 Days Room Temperature

                  14 days Refrigerated

                   2 Months  Frozen

Reference Values

Negative:          <21  %

Equivocal:      21 - 25  %

 Positive:           >25  %

Test Classification and CPT Coding

83519

 

LOINC Code: 30192-9

 

 

LONIC:  11562-6

Computer Interface Code

PDM # 5901705

Useful For

Diagnose myasthenia gravis (MG); monitor response to treatment of myasthenia gravis

Limitations

False positives can occur in patients with serum drawn within 48 hours of administration of general anesthesia and muscle relaxants. Antibodies to α-bungarotoxin (α-BTX) may sometimes be found in patients treated with snake venom. Recently administered radioisotopes may interfere with the assay in unpredictable ways. Acetylcholine receptor autoantibodies are not typically found in congenital myasthenia gravis.