Test Code 14-3 3 Protein TAU, CSF 14-3-3 Protein Tau, CSF
Performing Laboratory
National Prion Disease Pathology Surveillance Center (NPDPSC)
Methodology
Immunoassay • RT-QulC (real-time quaking-induced conversion)
Reference Values
RT-QulC Negative
T-Tau protein (CSF) 0 - 1149 pg/mL
14-3 3 protein (CSF) Negative
TAT: 21 Days
CPT Coding
84182
86317
0035U
LOINC code: 19146-0
Specimen Requirements
Collection Container/Tube: Sterile vial
Container/Tube: Plastic vial
Specimen Volume: 2-5 mL CSF(min 2 mL)
Stability Room temperature: 24 hours
Refrigerated: 14 days
Frozen: Indefinitely
Collection Instructions:
1. Obtain aliquot from second collection vial.
2. Hemolyzed specimens will give false-positive results. Specimens should be centrifuged to remove any red cells before shipping. The test will be canceled if there is any level of hemolysis present.
Transport Temperature: Frozen CSF
Additional Information:
1. Specimens that have not been kept refrigerated or that have been tested for other analytes previously may give a false-positive result.
2. Separate specimens should be submitted when multiple tests are ordered. This will reduce the risk of test cancellation due to stability problems.
Please send sample with requsuiton found in Resources.
Computer Interface Code
PDM # 1759541
Used For
Supporting, in conjunction with other tests, a diagnosis of Creutzfeldt-Jakob disease in patients with rapidly progressive dementia when other neurodegenerative conditions have been excluded