Voltage-Gated K Channel Ab VGKCAB

Synonyms

Allscripts (AEHR) Order Name

Voltage-Gated K Channel AB

Sunrise Clinical Manager (SCM) Order Name

Voltage-Gated K Channel Ab

Clinical Info

Voltage-Gated Potassium Channel (VGKC) antibodies are associated with neuromuscular weakness as found in neuromyotonia (also known as Issacs syndrome) and Morvan syndrome. VGKC antibodies are also associated with paraneoplastic neurological syndromes and limbic encephalitis; however, VGKC antibody-associated limbic encephalitis may be associated with antibodies to leucine-rich, glioma-inactivated 1 protein (Lgi1) or contactin-associated protein-2 (Caspr-2) instead of potassium channel antigens.The clinical significance of this test can only be determined in conjunction with the patient's clinical history and related laboratory testing.  

Specimen Type

Blood

Container

Red Top Tube

Collection Instructions

Container/Tube: Gold Top Tube
Specimen: 4 mL serum ( 1.0 mL min)
Transport Temperature: Refrigerated
Separate serum from cells within 1 hour.

Transport Instructions

Refrigerated

Specimen Stability

Room Temperature: 3 Days
Refrigerated : 2 weeks
Frozen: 1 Month

Methodology

Quantitative Radioimmunoassay

Days Performed

Tuesday
 
TAT: 2 - 9 Days

Performing Laboratory

ARUP Laboratories

CPT

83519

PDM

1559857

Result Interpretation

 

Negative 31 pmol/L or less
Indeterminate 32-87 pmol/L
Positive 88 pmol/L or greater

 

Forms


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