Thyroglobulin FNA THYROFNA

Synonyms

Allscripts (AEHR) Order Name

Not Orderable

Sunrise Clinical Manager (SCM) Order Name

Thyroglobulin FNA

Clinical Info

Clinically enlarged cervical lymph nodes with a history of thyroid cancer are usually assessed by fine-needle aspiration biopsy (FNAB) followed by a cytology. Thyroglobulin (Tg) is frequently elevated in malignant FNAB needle wash specimens and it's use may possibly augment or replace cytology

Specimen Type

Body Fluid

Container

Sterile

Collection Instructions

Container/Tube: Sterile transport container
Specimen: 1 mL Fine Needle Aspirate (FNA) of Lymph Node (min 0.8 mL FNA) Or Thyroid tissue washing
Transport Temperature: Frozen
Alternative Specimens Non-lymph node, non-nodal soft tissue, or cervical node washings

Collection Instructions

A 25-gauge needle is inserted obliquely within the transducer plane of view and moved back and forth (passes) through the nodule to compensate for patient movement and needle deflection. There is no suction device; cells move into the needle via capillary action. After collection of the cytology samples, withdraw between 0.10 and 0.25 mL of saline up through each needle and empty this fluid back through the needle into a tube. This is the needle washing used for analysis. Repeat the passes and saline washings from the same biopsied site and empty contents into the same tube. The washes from all needles are pooled (final volume 1 mL). Inspect specimen for visible blood or tissue contamination. If bloody, centrifuge specimen and transfer supernatant to a new tube to send to the laboratory. The supernatant, not the cellular materials, is used for analysis. If the specimen is clear, centrifugation is not necessary.

Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.

Transport Instructions

Frozen

Specimen Stability

14 Days Room Temperature
7 Days Refrigerated
28 Days Frozen

Methodology

Beckman Coulter Chemiluminescent

Days Performed

TAT: 5- 8 Days

Performing Laboratory

Quest Diagnostics' Nichols Institute, Inc. - Chantilly

CPT

84432
 
LOINC Code: 53922-1

PDM

5960070

Result Interpretation

Negative:	≤1.0 ng/mL
Indeterminate:	1.1-10.0 ng/mL
Consistent with thyroid tissue or metastatic thyroid cancer:	>10.0 ng/mL

Forms