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LDL Particles NMR, Plasma
NMR
Synonyms
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Allscripts (AEHR) Order Name
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NMR (Nuclear Magnetic Resonance) LipoProfile
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Sunrise Clinical Manager (SCM) Order Name
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NMR LipoProfile Plasma
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Clinical Info
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NMR LDL-P is a management tool used in appropriate high-risk patients (type 2 diabetes mellitus, metabolic syndrome, CVD risk equivalent, statin-treated patients) to adjudicate response to treatment and guide adjustment in therapy. It is used in conjunction with other lipid measurements and clinical evaluation to aid in the management of lipoprotein disorders associated with cardiovascular disease.
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Specimen Type
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Blood
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Container
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NMR LipoTube (black-and-yellow-top tube) is the preferred container, or plain red-top tube, or lavender-top (EDTA-no gel) tube, or green-top (heparin) tube.
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Collection Instructions
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Container/Tube: NMR LipoTube (black-and-yellow-top tube) is the preferred container, or plain red-top tube, or lavender-top (EDTA-no gel) tube, or green-top (heparin) tube.
Specimen: 2 mL serum ( 1 mL min)
Patient Preparation Patient should be fasting for 12 to 14 hours.
Collection
Collect specimen in NMR LipoTube (black-and-yellow-top tube), which is the preferred container. Plain red-top, green-top (heparin-no gel), or lavender-top (EDTA-no gel) tubes are also acceptable. Serum or plasma drawn in gel-barrier collection tubes other than the NMR LipoTube should not be used. The LipoTube is the only acceptable gel-barrier tube. Gently invert tube 8 to 10 times to mix contents and allow specimen to clot for 30 minutes upright at room temperature prior to centrifugation (Plasma tubes should not clot). Centrifuge specimen within two hours of collection at 1800xg for 10 to 15 minutes to separate serum/plasma from the red cells and to avoid red cell contamination during shipment. If the sample cannot be centrifuged immediately, the sample should be refrigerated (at 2ºC to 8ºC) and centrifuged within 24 hours of collection. Note: Centrifuging the specimen while still cold may negatively affect the migration of the gel to the serum/red cell interface and may increase the likelihood of specimens being contaminated with red cells during shipment. All specimens should be centrifuged by the client, prior to shipment to LabCorp, to ensure sample integrity. Do not open NMR LipoTube (black-and-yellow-top). Immediately after centrifugation, pipette separated red-top serum or green-top/lavender-top plasma into a transport tube and label accordingly (serum, heparin plasma, EDTA plasma)
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Transport Instructions
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Refrigerated
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Specimen Stability
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Unacceptable Room Temperature
6 Days Refrigerated
Unacceptable Frozen
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Methodology
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Nuclear magnetic resonance (NMR)
Test Includes Historical reporting (LDL-P, LDL-C); insulin-resistance score; lipoprotein particle number (LDL-P); particle concentration and size (total HDL-P, small LDL-P, LDL size); standard lipid panel (total cholesterol, calculated LDL cholesterol, HDL cholesterol, triglycerides).
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Days Performed
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Performing Laboratory
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LabCorp of America
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CPT
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80061
83704
LOINC Code: 91136-2
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PDM
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5906017
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Result Interpretation
See Report
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Forms
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