Mexiletine Level MEX

Synonyms

Allscripts (AEHR) Order Name

Mexiletine Level, Serum

Sunrise Clinical Manager (SCM) Order Name

Mexiletine Level, Serum

Clinical Info

Assessing achievement of optimal therapeutic concentrations
 
Assessing potential toxicity

Specimen Type

Blood

Container

Red Top Tube

Collection Instructions

Specimen Type: Serum Red
Patient Preparation: Samples should only be collected after patient has been receiving mexiletine for at least 3 days. Trough concentrations should be collected just before administration of the next dose.
Collection Container/Tube: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions:
1. Samples should only be collected after patient has been receiving mexiletine for at least 3 days.
2. Draw blood immediately before next scheduled dose.
3. Centrifuge within 2 hours of draw and aliquot to remove serum from spun RBCs.
Specimen Minimum Volume: 0.5 mL
Specimen Stability Information:

Specimen Type	Temperature	Time	Special Container
Serum Red	Refrigerated (preferred)	28 days
	Ambient	28 days
	Frozen	28 days

Transport Instructions

Specimen Stability

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Days Performed

Monday through Saturday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT

80299

PDM

5900985

Result Interpretation

Trough Value
0.5-2.0 mcg/mL: Therapeutic concentration
>2.0 mcg/mL: Toxic concentration

Forms