Librium (Chlordiazepoxide) LIBRIUM

Synonyms

Chlordiazepoxide

Allscripts (AEHR) Order Name

Chlordiazepoxide Level, Serum

Sunrise Clinical Manager (SCM) Order Name

Chlordiazepoxide Level, Serum

Clinical Info

Use to optimize dosing and monitor patient adherence.
Includes: Librium (Chlordiazepide)and Nordiazepam

Specimen Type

Blood

Container

Red Top Tube

Collection Instructions

Container/Tube: Red Top Tube or Gray Top Tube
Specimen: 2 mL Serum or Plasma (1 mL min)
Transport Temperature: Refrigerated
Centrifuge and aliquot serum into vial within 2 hours of collection.
Patient Preparation More information
Timing of specimen collection: Predose (trough) draw at steady state concentration.

Transport Instructions

Specimen Stability

1 Week Room Temperature
2 Weeks Refrigerated (preferred)
3 years Frozen

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Days Performed

TAT: 2 - 8 Days

Performing Laboratory

ARUP Laboratories

CPT

80346
(Atl Code; G0480)

PDM

5915200

Result Interpretation

Therapeutic concentration:

Chlordiazepoxide: 500-3,000 ng/mL-Dose (afult): 5-100 mg)

               Toxic: Greater than 5000 ng/mL

Nordiazepam: 100-500 ng/mL- Based ib normal doses

           Toxic: Greater than 2500 ng/mL

Forms