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Test Code LDHISO Lactate Dehydrogenase (LD) Isoenzyme Electrophoresis, Serum

Performing Laboratory

Quest Diagnostics' Nichols Institute, Inc. - Chantilly

Methodology

Electrophoresis

Reference Values

LD___________Males____Females
Age___________U/L_______U/L
< 1 month____ 125-735___ 145-765
_1-11 months_ 170-450___ 190-420
_1-_3 years___155-345___ 165-395
_4-_6 years___155-345___ 135-345
_7-10 years___140-270___ 140-270
11-13 years___110-250___ 110-250
14-17 years___110-230___ 110-230
18-49 years___100-220___ 100-200
 > 50 years____120-250___ 120-250
No age, either gender
_________________100-250 U/L___


 

LD Isoenzymes
LD1__19-38%
LD2__30-43%
LD3__16-26%
LD4__03-12%
LD5__03-14%


 

LD1/LD2 Ratio
The optimum decision threshold for the LD1/LD2 Ratio is, by ROC curve analysis, 0.93.

Test Classification and CPT Coding

83615 - LD

83625 - isoenzyme

Day(s) and Time(s) Performed

Monday through Friday, Sunday

Physician Office Specimen Requirements

Container/Tube:  Gold-top tube(s)

Specimen:  2 mL of serum

Transport Temperature:  Ambient

Useful For

Lactate Dehydrogenase (LD) is an enzyme that is present in many different organs and tissues. LD Isoenzymes (LDI) are useful in distinguishing the different isoenzymes expressed differentially in tissues and organs, e.g., cardiac muscle, skeletal muscle, and liver.

Computer Interface Code

PDM #  5300195