HLA Class A-B-C Disease Asso HLA-ABC

Synonyms

Allscripts (AEHR) Order Name

HLA Class A-B-C Disease Association

Sunrise Clinical Manager (SCM) Order Name

HLA Class A-B-C Disease Asso.

Clinical Info

Determining class I human leukocyte antigens (HLA) on specimens for those patients
who have become refractory to platelet transfusions and identify potential disease association
Human leukocyte antigens (HLA) are regulators of the immune response.
HLA class I typing is used to identify HLA-matched platelets for alloimmunized
refractory patients and identify presence of HLA antigens associated with a
number of diseases or as drug hypersensitivity markers Class I HLA antigens
include A, B, and C loci. This assay is designed to provide low-to-medium
resolution for HLA class I typing (A, B, C). Low-to-medium resolution defines
the typing at the antigen level (first field). This is in contrast to high-resolution
typing, which defines typing at the allele (molecular) level (second field or higher).

Specimen Type

Blood

Container

Acd/Yellow

Collection Instructions

Container/Tube: Yellow top (ACD solution B)
Specimen: 6 mL whole Blood ( 3 mL min)
Transport Temperature: Room Temperature
Instructions: Do not transfer blood to other containers.
Additional
Information: Specimen acceptability is based on extracted DNA
concentration and not sample age

Transport Instructions

Room Temperature

Specimen Stability

Methodology

Polymerase Chain Reaction (PCR)/Sequence-Specific Oligonucleotide Probes (SSO)

Days Performed

Performing Laboratory

Mayo Medical Laboratories
Mayo Code 1DIS

CPT

81372 (if all loci-A, B, C performed)
81373 (if appropriate for each loci if less than 3 performed)
LONIC Code: 96629-1

PDM

2059436

Result Interpretation

Forms