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Test Code EEEP Eastern Equine Encephalitis Antibody, IgG and IgM, Serum

Useful For

Aiding in the diagnosis of Eastern equine encephalitis

Method Name

Immunofluorescence Assay (IFA)

Reporting Name

East Equine Enceph Ab, IgG and IgM, S

Specimen Type


Specimen Required


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL

Specimen Minimum Volume

0.15 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Clinical Information

Eastern equine encephalitis (EEE) is within the alphavirus group. It is a low prevalence cause of human disease in the eastern and Gulf Coast states. EEE is maintained by a cycle of mosquito/wild bird transmission, peaking in the summer and early fall, when man may become an adventitious host. The most common clinically apparent manifestation is a mild undifferentiated febrile illness, usually with headache. Central nervous system involvement is demonstrated in only a minority of infected individuals, it is more abrupt and more severe with EEE than other arboviruses, with children being more susceptible to severe disease. Fatality rates are approximately 70% for EEE.

Reference Values

IgG: <1:10

IgM: <1:10

Day(s) and Time(s) Performed

May through October: Monday through Friday; 9 a..m.


November through April: Monday, Wednesday, Friday; 9 a.m.

Analytic Time

Same day/1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86652 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EEEP East Equine Enceph Ab, IgG and IgM, S 69034-7


Result ID Test Result Name Result LOINC Value
83354 East Equine Enceph Ab, IgG, S 10896-9
83355 East Equine Enceph Ab, IgM, S 10898-5

NY State Approved