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Test Code DHEAS Dehydroepiandrosterone Sulfate (DHEA-S), Serum

Performing Laboratory

Northwell Health Laboratories

Methodology

Competitive Chemiluminescent Immunoassay

Reference Values

MALES

1-14 days:  DHEA-S levels in newborns are very elevated at birth but will fall to prepubertal levels within a few days.

 

 

Tanner Stages* 

 

Mean Age

Reference Range (µg/dL)

     

Stage I

>14 days

<15-120

Stage II 

11.5 years

<15-333

Stage III 

13.6 years 

<15-312

Stage IV 

15.1 years 

29-412

Stage V 

18.0 years 

89-457

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (±2) years. For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) is usually reached by age 18.
 
18-29 years:  89-457 µg/dL
30-39 years:  65-334 µg/dL
40-49 years:  48-244 µg/dL
50-59 years:  35-179 µg/dL
≥60 years:  25-131 µg/dL
 

FEMALES

1-14 days:  DHEA-S levels in newborns are very elevated at birth but will fall to prepubertal levels within a few days. 

 

 

Tanner Stages* 

 

Mean Age

 Reference Range (µg/dL)

     

Stage I

>14 days 

16-96

Stage II 

10.5 years

22-184

Stage III 

11.6 years

<15-296

Stage IV 

12.3 years 

17-343

Stage V

 14.5 years

44-332

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for girls at a median age of 10.5 (±2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. Progression through Tanner stages is variable. Tanner stage V (adult) is usually reached by age 18.
 
18-29 years:  44-332 µg/dL
30-39 years:  31-228 µg/dL
40-49 years:  18-244 µg/dL
50-59 years:  <15-200 µg/mL

≥60 years:  <15-157 µg/dL

Test Classification and CPT Coding

Test Classification:

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer’s instructions.

CPT Code:

82627

Physician Office Specimen Requirements

Container/Tube:  Plain, red-top tube(s) or serum gel tube(s)

Specimen:  0.8 mL (minimum volume:  0.25 mL) of serum

Transport Temperature:  Refrigerate

Day(s) and Time(s) Performed

Monday through Friday

Computer Interface Code

PDM # 5900535