CD56 CD56

Synonyms

Allscripts (AEHR) Order Name

Not Orderable

Sunrise Clinical Manager (SCM) Order Name

Not Orderable

Clinical Info

Aiding in the identification of tumors with neuroendocrine differentiation
 
Aiding in the identification of natural killer cell lineage in a subset of lymphomas
CD56 is an adhesion molecule mediating homophilic and heterophilic adhesion in neurons, natural killer cells, and a small subset of CD4- and CD8-positive T cells. It is expressed in tumors with neuroendocrine differentiation (small cell lung carcinoma and neural-derived tumors) or natural killer cell lineage (subset of lymphomas). In normal small intestine, the ganglion cells in the muscle wall and nerves will show strong staining. Scattered lymphocytes may also be positive.

Specimen Type

Tissue, Bone Marrow, Body Fluid, CSF, Blood, Swab

Container

Green Top Tube

Collection Instructions

Specimen Type: TECHONLY
Supplies: Immunostain Technical Only Envelope (T693)
Specimen Type: Tissue
Container/Tube: Immunostain Technical Only Envelope
Preferred: 2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.
Acceptable: Formalin-fixed, paraffin-embedded (FFPE) tissue block
Specimen Minimum Volume:
Specimen Stability Information:

Specimen Type	Temperature	Time	Special Container
TECHONLY	Ambient (preferred)
	Refrigerated

Transport Instructions

Specimen Stability

Methodology

Immunohistochemistry

Days Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT

88342-TC, primary
88341-TC, if additional IHC

PDM

5200230

Result Interpretation

Forms