CD10 CD10

Synonyms

Allscripts (AEHR) Order Name

Not Orderable

Sunrise Clinical Manager (SCM) Order Name

Not Orderable

Clinical Info

Phenotyping leukemias and lymphomas
CD10 is a cell surface glycoprotein present on bone marrow B precursors (hematogones) and myeloid cells (including neutrophils), 
follicle center B cells, and a subset of follicular T helper cells. CD10 is also expressed in the brush border of the upper part of the 
intestinal tract, bile canaliculi, kidney (glomerular and proximal tubular cells), pulmonary alveolar cells, myoepithelial cells of breast, 
prostate glandular cells, placental trophoblastic cells, endometrial stromal cells, some endothelial cells, and a minority of (myo-)fibroblasts 
(stromal cells). CD10 is most useful in the diagnosis of B-precursor-acute lymphoblastic leukemia, Burkitt lymphoma, and lymphomas of 
follicle cell center origin (follicular lymphoma, subset of large B-cell lymphomas).

Specimen Type

Tissue, Bone Marrow, Body Fluid, CSF, Blood, Swab

Container

Immunostain Technical Only Envelope

Collection Instructions

Specimen Type: TECHONLY
Supplies: Immunostain Technical Only Envelope (T693)
Specimen Type: Tissue
Container/Tube: Immunostain Technical Only Envelope
Preferred: 2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered;
sections 4-microns thick
Acceptable: Formalin-fixed, paraffin-embedded (FFPE) tissue block
Specimen Minimum Volume:
Specimen Stability Information:
Specimen TypeTemperatureTimeSpecial ContainerTECHONLYAmbient (preferred) Refrigerated 

Transport Instructions

Specimen Stability

Methodology

Immunohistochemistry

Days Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT

88342-TC, primary
88341-TC, if additional IHC

PDM

5200060

Result Interpretation

This test does not include pathologist interpretation; only technical performance of the stain is performed. If an interpretation is required, order PATHC / Pathology Consultation for a full diagnostic evaluation or second opinion of the case.

The positive and negative controls are verified as showing appropriate immunoreactivity and documentation is retained at Mayo Clinic Rochester. If a control tissue is not included on the slide, a scanned image of the relevant quality control tissue is available upon request. Contact 855-516-8404.

Interpretation of this test should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.

Forms

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