Prostatic Acid Phosphatase PAP

Synonyms
Allscripts (AEHR) Order Name	Prostatic Acid Phosphatase, Serum
Sunrise Clinical Manager (SCM) Order Name	Prostatic Acid Phosphatase, Serum
Clinical Info	An adjunct in the evaluation of possible prostatic malignancy and useful in monitoring therapeutic progress This test is not the same as Acid Phosphatase. Values obtained with different assays should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy. This procedure does not provide serial monitoring; it is intended for one-time use only.
Specimen Type	Blood
Container	Red Top Tube
Collection Instructions	Container/Tube: Gold Top Tube Specimen: 0.5 mL serum (0.3 mL min) Transport Temperature: Frozen
Transport Instructions	Refrigerated
Specimen Stability	3 Hours Room Temperature 24 Hours Refrigerated 6 Months Frozen
Methodology	Immunochemiluminometric assay (ICMA)
Days Performed	TAT: 3-4 Days
Performing Laboratory	LabCorp
CPT	84066 LOINC Code: 20420-6
PDM	5900130
Result Interpretation 0−3.5 ng/mL Prostatic acid phosphatase has been used as a tumor marker ever since the observation by Gutman in 1938¹ that elevated levels of this enzyme are found in patients with metastatic prostate cancer. PAP determination in conjunction with PSA measurements is useful in assessing the prognosis of prostate cancer.² Measurement of two markers allows identification of prostate cancer patients who have an elevation of PAP but not of PSA, and thus help monitoring the course of disease and response to treatment. PAP is more specific than PSA and less false-positives are seen due to benign prostatic hyperplasia.
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