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BCR/ABL, Translocation 9;22, D-FISH

Performing Laboratory

Northwell Health Laboratories

Methodology

Fluorescence In Situ Hybridization (FISH)

Reference Values

See report.

Test Classification and CPT Coding

88271 x 2 - DNA probe, each

88275 x 2 - interphase in situ hybridization

88291 - interpretation and report

Day(s) and Time(s) Performed

Monday through Sunday

Physician Office Specimen Requirements

Please provide a reason for referral with each specimen. The laboratory will not delay or reject testing if this information is not provided, but appropriate testing and interpretation may be compromised.

 

Submit only 1 of the following specimens:


Blood

Container/Tube:  Green-top (sodium heparin) tube(s) - Clotted blood is not acceptable.

Specimen:  7 mL to 10 mL (minimum volume:  2 mL) of sodium heparin whole blood.

Transport Temperature:  Ambient

Collection Instructions:  Invert several times to mix blood. Other anticoagulants are not recommended and are harmful to the viability of the cells. Label vial with patient’s name and laboratory control number. Forward promptly. Specimen cannot be frozen.

Note:  1. Indicate blood on request form.
2. Label specimen appropriately (blood).

 

Bone Marrow

Obtain 1 mL to 2 mL (minimum volume:  1 mL) of bone marrow in a green-top (sodium heparin) tube(s). Invert several times to mix bone marrow. (Clotted bone marrow is not acceptable.) Other anticoagulants are not recommended and are harmful to the viability of the cells. Label vial with patient’s name and laboratory control number. Forward promptly at ambient temperature. Specimen cannot be frozen.

Note:  1. Indicate bone marrow on request form.
2. Label specimen appropriately (bone marrow).